The Structure and Function of Natural Proteins and Maquettes

Symposium in honor of P. Leslie Dutton
Friday, May 31st & Saturday, June 1st
Program

Friday, May 31st 2019
Glen Gaulton Auditorium, BRB II, 421 Curie Blvd., Philadelphia, PA 19104
8:00 – 9:00 am
Breakfast
Session 1A: Natural and Artificial Photosynthesis
9:00 – 9:15 am
Katsumi Matsuura
Tokyo Metropolitan University, Japan
Electron transfer through hydrogen, sulfur, and nitrogen in thermophilic photosynthetic and chemosynthetic microbial communities
9:15 – 9:30 am
Dan Robertson
Joule Unlimited Technologies
Light utilization by photosynthetic cultures
9:30 – 9:45 am
David Tiede
Argonne National Lab
Tracking photons-to-fuels across natural and artificial photosynthesis
9:45 – 10:00 am
David Officer
Univ. of Wollongong, Australia
Energy Conversion Using synthetic protein/porphyrin ensembles
10:00 – 10:15 am
Dror Noy
Galilee Research Inst., Israel
Natural chlorophyll-binding protein maquettes
10:15 – 10:30 am
Nathan Ennist
University of Washington
Designing LH2-like chlorophyll-binding proteins for efficient energy transfer
10:30 – 10:50 am
Neil Hunter
University of Sheffield, UK
Two for the price of one: engineering singlet fission within a maquette framework
10:50 – 11:05 am
Elisabet Romero
Institute of Chemical Research of Catalonia, Spain
Quantum coherent maquettes
Session 1B: Data Science
11:05 – 11:15 am
Zhenyu Zhao
Airbnb / formerly Microsoft
Smart notes composing for customer support agents using neural abstractive summarization

11:30 am - 1:30 pm
Lunch on 14th floor BRB II, 421 Curie Blvd., Philadelphia, PA 19104

Session 2: Natural Protein Function
1:30 – 1:45 pm
Marilyn Gunner
City College of New York
Thinking about how proton pumps pump protons
1:45 – 2:05 pm
Tony Moore
University of Sussex, UK
Structure and function of the alternative oxidases: parasite saviour or human life saver?
2:05 – 2:20 pm
Artur Osyczka
Jagiellonian Univ., Poland
Understanding molecular processes in quinol oxidoreductases of respiration and photosynthesis
2:20 – 2:35 pm
Jose Cerda
St. Joseph University
Molecular mechanisms in heme protein function: A thermodynamic perspective from fluoride binding studies
2:35 – 2:50 pm
Kurt Warncke
Emory University
From within to without: Mechanism and context of a bacterial microcompartment signature enzyme
2:50 – 3:05 pm
Huangen Ding
Louisiana State University
Electron transfer activity of mitoNEET in mitochondrial outer membrane

3:05 – 4:00 pm
Coffee break

Session 3: Advancing Medicine and Materials
4:00 – 4:15 pm
Martin Iwanicki
University of Pennsylvania
Using maquettes to read the mind
4:15 – 4:30 pm
Dirk Auman
University of Pennsylvania
Engineered protein oxygen carriers: a novel blood substitute for emergency care
4:30 – 4:45 pm
Bruce Lichtenstein
Univ. of Bayreuth, Germany
Clarifying the natural engineering of AB5 toxins towards a new platform for biomolecular delivery
4:45 – 5:00 pm
Shixin Ye
Sorbonne University, France
Unnatural amino acids highlight specificity of signalling transduction
5:00 – 5:15 pm
Sara Dutton Sackett
University of Wisconsin
Probing the human pancreas and Islet matrisome for matrix-stem cell-derived islet interactions
5:15– 5:30 pm
Steve Huang
Cleveland Clinic
Targeting prostate cancer
5:30 – 5:45 pm
Xiaoxi (Kevin) Chen
Medical Surface, Inc.
Engineering the bio/material interface for implantable and wearable glucose sensors
5:45 – 6:00 pm
Lee Solomon
Science and Technology Policy, AAAS
Engineering function into a peptide-based material
6:00 – 6:15 pm
Joseph Strzalka
Argonne National Lab
From Penn to the APS: In situ studies of proteins and organic optoelectronic materials

6:30 - 8:45 pm
Apéros and Dinner
In front of the Glen Gaulton Auditorium, BRB II, 421 Curie Blvd., Philadelphia, PA 19104



Saturday, June 1st 2019
Jordan Medical Education Center, 3400 Civic Center Blvd, Philadelphia, PA 19104
8:00 – 9:00 am
Breakfast
Session 4: Designing Protein Function
9:00 – 9:15 am
Vikas Nanda
Rutgers University
Modular origins of oxidoreductases
9:15 – 9:35 am
P. Leslie Dutton
University of Pennsylvania
Quantum mechanics of oxidoreductases
9:35 – 9:50 am
Ross Anderson
University of Bristol, UK
Catalysis in maquettes: Les is more...
9:50 – 10:05 am
Ronald Koder
City College of New York
Using dynamics and supercharging to design functional proteins
10:05 – 10:20 am
Brian R. Gibney
Brooklyn College
Using ferredoxin maquettes to probe zinc finger protein folding

10:20 – 11:20 am
Coffee break

11:20 – 11:35 am
Julia Shifman
Hebrew University, Israel
Protein-protein interactions: from evolution to design
11:35 – 11:50 am
Christopher Moser
University of Pennsylvania
No-fuss biological electron transfer
11:50 – 12:05 pm
Anne Katherine Jones
Arizona State University
Electrocatalysis and enzymology
12:05 – 12:20 pm
Joshua Mancini
Rutgers University
Searching for potential metallopeptide based hydrogenases capable of activity on an Archean Earth

12:30 pm
Bus departure for a special gathering at Les’s house
6:00 pm
Bus departure from Les’s house to AKA, 2929 Walnut St, Philadelphia, PA 19104